Virus‐Surface‐Mimicking Surface Clustering of AuNPs onto DNA‐Entrapped Polymeric Nanoparticle for Enhanced Cellular Internalization and Nanocluster‐Induced NIR Photothermal Therapy
نویسندگان
چکیده
Virus-surface-mimicking decoration of deoxyribonucleic acid (DNA)-entrapped polymeric nanoparticle with AuNPs is demonstrated to lead to enhanced cellular uptake, improved gene transfection, and particularly efficient near-infrared photothermal therapy that cannot be achieved by both of them separately. This hybrid nanosystem represents a novel paradigm of multipurpose organic-inorganic nanoplatform, especially for cancer treatments.
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2015